Blar i forfatter "Peterson, Kevin J."

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    • Accurate microRNA annotation of animal genomes using trained covariance models of curated microRNA complements in MirMachine 

      Umu, Sinan Ugur; Paynter, Vanessa Molin; Trondsen, Håvard; Buschmann, Tilo; Rounge, Trine Ballestad; Peterson, Kevin J.; Fromm, Bastian (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-23)
      The annotation of microRNAs depends on the availability of transcriptomics data and expert knowledge. This has led to a gap between the availability of novel genomes and high-quality microRNA complements. Using >16,000 microRNAs from the manually curated microRNA gene database MirGeneDB, we generated trained covariance models for all conserved microRNA families. These models are available in our ...

    • MicroRNAs are deeply linked to the emergence of the complex octopus brain 

      Zolotarov, Grygoriy; Fromm, Bastian; Legnini, Ivano; Ayoub, Salah; Polese, Gianluca; Maselli, Valeria; Chabot, Peter J.; Vinther, Jakob; Styfhals, Ruth; Seuntjens, Eve; Di Cosmo, Anna; Peterson, Kevin J.; Rajewsky, Nikolaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-25)
      Soft-bodied cephalopods such as octopuses are exceptionally intelligent invertebrates with a highly complex nervous system that evolved independently from vertebrates. Because of elevated RNA editing in their nervous tissues, we hypothesized that RNA regulation may play a major role in the cognitive success of this group. We thus profiled messenger RNAs and small RNAs in three cephalopod species ...